منابع مشابه
Primary cilia
The primary cilium was first so named by Sergei Sorokin in 1968.[1] Since the discovery of primary cilium in 1898 by Zimmerman, three major hypotheses for their function have been put forth. The first is that primary cilia are vestigial organelles inherited from an ancestor whose cells had motile cilia and now are of no purpose in multicellular organisms. The second is that they are involved in...
متن کاملCilia graft.
Numerous aetiological factors can be involved in loss of eyelid substance and ideally, wherever possible, such deficits are closed by primary anastomosis. However, in the presence of extensive trauma, tumour formation, or congenital anomaly, a number of reconstructive techniques may have to be employed. These are outlined elsewhere (Smith, I959; Smith and English, 1970), but briefly to recapitu...
متن کاملCilia signaling
Cilia signaling I t takes well-built cilia to send developmental signals on their way, show Tamara Caspary, Kathryn Anderson (Sloan-Kettering Institute, New York, NY), and Christine Larkins (Emory University, Atlanta, GA). Cilia that lack the correct internal architecture fail to transduce Hedgehog (Hh) signals correctly. Hh signaling is particularly well-characterized in the developing nervous...
متن کاملA "so cilia" network: cilia proteins start "social" networking.
Cilia are unique cellular organelles found in nearly all cell types. In recent years, the importance of these organelles has been highlighted by the discovery that mutations in genes encoding proteins related to cilia biogenesis and function cause a class of complex syndromes termed ciliopathies. Emerging evidence suggests interactions among the various ciliopathy-associated proteins, but the p...
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ژورنال
عنوان ژورنال: Nature
سال: 1979
ISSN: 0028-0836,1476-4687
DOI: 10.1038/278018a0